Cytology of soft tissue tumors: Malignant small round cell tumors

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Cytogenetics and tissue culture of small round cell tumors of bone and soft tissue.

The variety of tumor-specific cytogenetic and genetic alterations among small round cell tumors (Ewing family of tumors, rhabdomyosarcoma, neuroblastoma, and lymphoma) increases the possibility of genotypic diagnosis of them. In Ewing's sarcoma and related peripheral primitive neuroectodermal tumors, a (11;22)(q24;q12) translocation is associated with hybrid transcripts of the EWS gene with the...

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Prevalence of Malignant Soft Tissue Tumors inExtremities: An Epidemiological Study in Syria

Background:   Although the majority of soft tissue masses are benign, it is important to consider malignancy in differential diagnoses. Because most soft tissue sarcomas present as a painless mass, clinicians must watch for signs suggestive of malignancy, including large size, rapid growth, and site deep into the deep fascia.The purpose of this study was to determine the relative prevalence acc...

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PAX7 Expression in Rhabdomyosarcoma, Related Soft Tissue Tumors, and Small Round Blue Cell Neoplasms.

Rhabdomyosarcoma, the most common soft tissue malignancy of childhood, is a morphologically variable tumor defined by its phenotype of skeletal muscle differentiation. The diagnosis of rhabdomyosarcoma often relies in part on the identification of myogenic gene expression using immunohistochemical or molecular techniques. However, these techniques show imperfect sensitivity and specificity, par...

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Differential diagnosis of small round cell tumors.

The differential diagnosis of small round cell tumors includes not only the small round cell tumors of infancy and childhood, but a variety of mesenchymal, cutaneous, and lymphoreticular neoplasms that may occur in adults as well as children. Moreover, lesions considered to be the classical small round cell tumors of childhood may occasionally occur in adults, and lesions characteristically see...

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Fine needle aspiration cytology of soft tissue tumors.

OBJECTIVE To review of the value of fine needle aspiration (FNA) cytology in the diagnosis of soft tissue tumors (STT). STUDY DESIGN A review of the literature was coupled with the authors' experience with indications, diagnostic specificity and pitfalls; clinical information; and the final cytology report. RESULTS Over the last few years, FNA has come to be considered a valuable tool in th...

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ژورنال

عنوان ژورنال: Journal of Cytology

سال: 2008

ISSN: 0970-9371

DOI: 10.4103/0970-9371.44038